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Novel Role of TGF-β in Differential Astrocyte-TIMP-1 Regulation: Implications for HIV-1-Dementia and Neuroinflammation
Astrocyte production of tissue inhibitor of metalloproteinase (TIMP)-1 is important in central nervous system (CNS) homeostasis and inflammatory diseases such as HIV-1-associated dementia (HAD). TIMPs and matrix metalloproteinases (MMPs) regulate the remodeling of the extracellular matrix. An imbala...
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Huvudupphovsmän: | , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
2006
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820372/ https://ncbi.nlm.nih.gov/pubmed/16496359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.20787 |
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