High-resolution mapping of nucleoprotein complexes by site-specific protein-DNA photocrosslinking: organization of the human TBP-TFIIA-TFIIB-DNA quaternary complex.

Eitemau Tebyg

• Interactions of a DNA-bound Transcriptional Activator with the TBP-TFIIA-TFIIB-Promoter Quaternary Complex()
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• TBP binds the transcriptionally inactive TA5 sequence but the resulting complex is not efficiently recognised by TFIIB and TFIIA.
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• Determination of the orientation of a DNA binding motif in a protein-DNA complex by photocrosslinking.
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• The transcriptional corepressor DSP1 inhibits activated transcription by disrupting TFIIA-TBP complex formation.
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• Nonradioactive, ultrasensitive site-specific protein–protein photocrosslinking: interactions of α-helix 2 of TATA-binding protein with general transcription factor TFIIA and transcriptional repressor NC2
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  Cyhoeddwyd: (2008)