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A gene signature based method for identifying subtypes and subtype-specific drivers in cancer with an application to medulloblastoma

BACKGROUND: Subtypes are widely found in cancer. They are characterized with different behaviors in clinical and molecular profiles, such as survival rates, gene signature and copy number aberrations (CNAs). While cancer is generally believed to have been caused by genetic aberrations, the number of...

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Auteurs principaux: Chen, Peikai, Fan, Yubo, Man, Tsz-kwong, Hung, YS, Lau, Ching C, Wong, Stephen TC
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820164/
https://ncbi.nlm.nih.gov/pubmed/24564171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S18-S1
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