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Microglia are the major source of TNF-α and TGF-β in postnatal glial cultures; regulation by cytokines, lipopolysaccharide, and vitronectin

Damage to the central nervous system (CNS) leads to increased production of TNF-α and TGF-β1, cytokines that have pro- or anti-inflammatory actions, respectively. To define whether astrocytes or microglia express these cytokines, prior studies have used mixed glial cultures (MGC) to represent astroc...

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Bibliografiske detaljer
Main Authors: Welser-Alves, Jennifer V., Milner, Richard
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819935/
https://ncbi.nlm.nih.gov/pubmed/23619393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2013.04.007
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