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Interaction of Calcium-bound C-reactive Protein with Fibronectin Is Controlled by pH: IN VIVO IMPLICATIONS()
C-reactive protein (CRP) binds with high affinity to fibronectin (Fn), a major component of the extracellular matrix (ECM), but at physiological pH the binding is inhibited by calcium ions (Ca(2+)). Because CRP circulates in the blood in Ca(2+)-bound form, the occurrence of CRP-Fn interactions in vi...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3819716/ https://ncbi.nlm.nih.gov/pubmed/15456743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M409054200 |
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