The N-terminal cytoplasmic region of NCBE displays features of an intrinsic disordered structure and represents a novel target for specific drug screening

The sodium dependent bicarbonate transporter NCBE/NBCn2 is predominantly expressed in the central nervous system (CNS). The highest protein concentrations are found in the choroid plexus. The primary function of this integral plasma membrane transport protein is to regulate intracellular neuronal pH...

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Hlavní autoři: Bjerregaard-Andersen, Kaare, Perdreau-Dahl, Harmonie, Guldsten, Hanne, Praetorius, Jeppe, Jensen, Jan K., Morth, Jens P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819638/
https://ncbi.nlm.nih.gov/pubmed/24223558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00320
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