Molecular Characterization of Patient-Derived Human Pancreatic Tumor Xenograft Models for Preclinical and Translational Development of Cancer Therapeutics

Preclinical evaluation of novel cancer agents requires models that accurately reflect the biology and molecular characteristics of human tumors. Molecular profiles of eight pancreatic ductal adenocarcinoma patient tumors were compared to corresponding passages of xenografts obtained by grafting tumo...

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Bibliographische Detailangaben
Hauptverfasser: Mattie, Mike, Christensen, Ashley, Chang, Mi Sook, Yeh, William, Said, Suzanne, Shostak, Yuriy, Capo, Linnette, Verlinsky, Alla, An, Zili, Joseph, Ingrid, Zhang, Yi, Kumar-Ganesan, Sathish, Morrison, Karen, Stover, David, Challita-Eid, Pia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819630/
https://ncbi.nlm.nih.gov/pubmed/24204193
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