Defining cardiac adaptations and safety of endurance training in patients with m.3243A>G-related mitochondrial disease()()()

BACKGROUND: Cardiac hypertrophic remodelling and systolic dysfunction are common in patients with mitochondrial disease and independent predictors of morbidity and early mortality. Endurance exercise training improves symptoms and skeletal muscle function, yet cardiac adaptations are unknown. METHOD...

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Main Authors: Bates, Matthew G.D., Newman, Jane H., Jakovljevic, Djordje G., Hollingsworth, Kieren G., Alston, Charlotte L., Zalewski, Pawel, Klawe, Jacek J., Blamire, Andrew M., MacGowan, Guy A., Keavney, Bernard D., Bourke, John P., Schaefer, Andrew, McFarland, Robert, Newton, Julia L., Turnbull, Douglass M., Taylor, Robert W., Trenell, Michael I., Gorman, Gráinne S.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819621/
https://ncbi.nlm.nih.gov/pubmed/23742928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2013.05.062
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