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Blood-brain transfer of Pittsburgh compound B in humans

In the labeled form, the Pittsburgh compound B (2-(4′-{N-methyl-[(11)C]}methyl-aminophenyl)-6-hydroxy-benzothiazole, [(11)C]PiB), is used as a biomarker for positron emission tomography (PET) of brain β-amyloid deposition in Alzheimer's disease (AD). The permeability of [(11)C]PiB in the blood-...

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Bibliografske podrobnosti
Main Authors: Gjedde, Albert, Aanerud, Joel, Braendgaard, Hans, Rodell, Anders B.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819578/
https://ncbi.nlm.nih.gov/pubmed/24223554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2013.00070
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