Targeted Inactivation of Dipeptidyl Peptidase 9 Enzymatic Activity Causes Mouse Neonate Lethality

Dipeptidyl Peptidase (DPP) 4 and related dipeptidyl peptidases are emerging as current and potential therapeutic targets. DPP9 is an intracellular protease that is regulated by redox status and by SUMO1. DPP9 can influence antigen processing, epidermal growth factor (EGF)-mediated signaling and tumo...

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Main Authors: Gall, Margaret G., Chen, Yiqian, Vieira de Ribeiro, Ana Julia, Zhang, Hui, Bailey, Charles G., Spielman, Derek S., Yu, Denise M. T., Gorrell, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819388/
https://ncbi.nlm.nih.gov/pubmed/24223149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078378
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