Bone Marrow Deficiency of MCPIP1 Results in Severe Multi-Organ Inflammation but Diminishes Atherogenesis in Hyperlipidemic Mice

OBJECTIVE: MCPIP1 is a newly identified protein that profoundly impacts immunity and inflammation. We aim to test if MCPIP1 deficiency in hematopoietic cells results in systemic inflammation and accelerates atherogenesis in mice. APPROACH AND RESULTS: After lethally irradiated, LDLR(−/−) mice were t...

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מידע ביבליוגרפי
Main Authors: Yu, Fang, Du, Fen, Wang, Yuzhen, Huang, Shengping, Miao, Ruidong, Major, Amy S., Murphy, E. Angela, Fu, Mingui, Fan, Daping
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3819309/
https://ncbi.nlm.nih.gov/pubmed/24223214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080089
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