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Association between mutation of the NF2 gene and monosomy 22 in menopausal women with sporadic meningiomas

BACKGROUND: Meningioma was the first solid tumor shown to contain a recurrent genetic alteration e.g. monosomy 22/del(22q), NF2 being the most relevant gene involved. Although monosomy 22/del(22q) is present in half of all meningiomas, and meningiomas frequently carry NF2 mutations, no study has bee...

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Autori principali: Tabernero, MariaDolores, Jara-Acevedo, María, Nieto, Ana B, Caballero, Arancha Rodríguez, Otero, Álvaro, Sousa, Pablo, Gonçalves, Jesús, Domingues, Patricia H, Orfao, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818970/
https://ncbi.nlm.nih.gov/pubmed/24171707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-114
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