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Clinical experience and critical evaluation of the role of everolimus in advanced renal cell carcinoma
The efficacy of sequential everolimus, an orally administered inhibitor of mammalian target of rapamycin (mTOR), was proven in a placebo-controlled phase III study, where median progression-free survival was 4.9 vs 1.9 months for placebo (hazard ratio: 0.33, P < 0.001). Placebo crossovers (80%) c...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Dove Medical Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818936/ https://ncbi.nlm.nih.gov/pubmed/24198635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OAJU.S13283 |
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