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Clinical experience and critical evaluation of the role of everolimus in advanced renal cell carcinoma

The efficacy of sequential everolimus, an orally administered inhibitor of mammalian target of rapamycin (mTOR), was proven in a placebo-controlled phase III study, where median progression-free survival was 4.9 vs 1.9 months for placebo (hazard ratio: 0.33, P < 0.001). Placebo crossovers (80%) c...

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Bibliografiske detaljer
Main Authors: Sun, Maxine, Abdollah, Firas, Schmitges, Jan, Jeldres, Claudio, Shariat, Shahrokh F, Perrotte, Paul, Karakiewicz, Pierre I
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818936/
https://ncbi.nlm.nih.gov/pubmed/24198635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OAJU.S13283
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