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Pazopanib and anti-VEGF therapy

Pazopanib (Votrient™, GlaxoSmithKline), a multi-kinase inhibitor with activity against VEGFR and other receptors, was recently approved by the FDA for the treatment of advanced renal cell carcinoma (RCC). Here, we review the history of its development, together with an overview of VEGF and its recep...

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Detalhes bibliográficos
Autor principal: Drabkin, Harry A
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818876/
https://ncbi.nlm.nih.gov/pubmed/24198612
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