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What Goes around Comes around-A Comparative Study of the Influence of Chemical Modifications on the Antimicrobial Properties of Small Cyclic Peptides

Tryptophan and arginine-rich cyclic hexapeptides of the type cyclo-RRRWFW combine high antibacterial activity with rapid cell killing kinetics, but show low toxicity in human cell lines. The peptides fulfil the structural requirements for membrane interaction such as high amphipathicity and cationic...

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Detalhes bibliográficos
Main Authors: Scheinpflug, Kathi, Nikolenko, Heike, Komarov, Igor V., Rautenbach, Marina, Dathe, Margitta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818835/
https://ncbi.nlm.nih.gov/pubmed/24276422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph6091130
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