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Notch-driven carcinogenesis: The merging of hepatocellular cancer and cholangiocarcinoma into a common molecular liver cancer subtypes

BACKGROUND & AIMS: The Notch signaling pathway is activated in leukemia and solid tumors (such as lung cancer), but little is known about its role in liver cancer. METHODS: The intracellular domain of Notch was conditionally expressed in hepatoblasts and their progeny (hepatocytes and cholangioc...

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Detalhes bibliográficos
Main Authors: Razumilava, Nataliya, Gores, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818720/
https://ncbi.nlm.nih.gov/pubmed/23352938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2013.01.017
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