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Amylin deposition in the brain: a second amyloid in Alzheimer’s disease ?
OBJECTIVES: Hyperamylinemia, a common pancreatic disorder in obese and insulin resistant patients, is known to cause amylin oligmerization and cytotoxicity in pancreatic islets leading to β-cell mass depletion and development of type-2 diabetes. Recent data revealed that hyperamylinemia also affects...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818462/ https://ncbi.nlm.nih.gov/pubmed/23794448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23956 |
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