Epigenetic Profiles in Children with a Neural Tube Defect; A Case-Control Study in Two Populations

Folate deficiency is implicated in the causation of neural tube defects (NTDs). The preventive effect of periconceptional folic acid supplement use is partially explained by the treatment of a deranged folate-dependent one carbon metabolism, which provides methyl groups for DNA-methylation as an epi...

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Main Authors: Stolk, Lisette, Bouwland-Both, Marieke I., van Mill, Nina H., Verbiest, Michael M. P. J., Eilers, Paul H. C., Zhu, Huiping, Suarez, Lucina, Uitterlinden, André G., Steegers-Theunissen, Régine P. M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818348/
https://ncbi.nlm.nih.gov/pubmed/24223810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078462
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