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Identification of RASAL1 as a Major Tumor Suppressor Gene in Thyroid Cancer
BACKGROUND: RAS-coupled MAPK and PI3K pathways play a fundamental role in thyroid tumorigenesis, and classical genetic alterations upregulating these pathways are well characterized. We hypothesized that gene abnormality of negative modulators of these signaling pathways might be an important altern...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818169/ https://ncbi.nlm.nih.gov/pubmed/24136889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt249 |
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