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Identification of RASAL1 as a Major Tumor Suppressor Gene in Thyroid Cancer

BACKGROUND: RAS-coupled MAPK and PI3K pathways play a fundamental role in thyroid tumorigenesis, and classical genetic alterations upregulating these pathways are well characterized. We hypothesized that gene abnormality of negative modulators of these signaling pathways might be an important altern...

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Main Authors: Liu, Dingxie, Yang, Chongfei, Bojdani, Ermal, Murugan, Avaniyapuram Kannan, Xing, Mingzhao
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818169/
https://ncbi.nlm.nih.gov/pubmed/24136889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt249
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