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Identification of RASAL1 as a Major Tumor Suppressor Gene in Thyroid Cancer
BACKGROUND: RAS-coupled MAPK and PI3K pathways play a fundamental role in thyroid tumorigenesis, and classical genetic alterations upregulating these pathways are well characterized. We hypothesized that gene abnormality of negative modulators of these signaling pathways might be an important altern...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818169/ https://ncbi.nlm.nih.gov/pubmed/24136889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt249 |
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