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Aggregatibacter actinomycetemcomitans biofilm killing by a targeted ciprofloxacin prodrug
A pH-sensitive ciprofloxacin prodrug was synthesized and targeted against biofilms of the periodontal pathogen Aggregatibacter actinomycetemcomitans (Aa). The dose required to reduce the viability of a mature biofilm of Aa by ~80% was in the range of ng cm(−2) of colonized area (mean biofilm density...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818142/ https://ncbi.nlm.nih.gov/pubmed/23952779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08927014.2013.823541 |
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