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Cloning, purification and preliminary crystallographic analysis of the complex of Helicobacter pylori α-carbonic anhydrase with acetazolamide

Helicobacter pylori infection of the stomach can lead to severe gastroduodenal diseases such as gastritis, peptic ulcers and gastric cancers. Periplasmic H. pylori α-carbonic anhydrase (HpαCA) is essential for the acclimatization of the bacterium to the acidity of the stomach. Through the action of...

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Bibliographische Detailangaben
Hauptverfasser: Modak, Joyanta K., Revitt-Mills, Sarah A., Roujeinikova, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818046/
https://ncbi.nlm.nih.gov/pubmed/24192362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113026146
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