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β-arrestin 2 knockout mice exhibit sensitized dopamine release and increased reward in response to a low dose of alcohol
RATIONALE: The rewarding effects of alcohol have been attributed to interactions between opioid and dopaminergic system within the mesolimbic reward pathway. We have previously shown that ablation of β-arrestin 2 (Arrb2), a crucial regulator of μ-opioid receptor function, attenuates alcohol-induced...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3817962/ https://ncbi.nlm.nih.gov/pubmed/23779257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3166-x |
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