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Release from meiotic arrest in ascidian eggs requires the activity of two phosphatases but not CaMKII

The fertilising sperm triggers a transient Ca(2+) increase that releases eggs from cell cycle arrest in the vast majority of animal eggs. In vertebrate eggs, Erp1, an APC/C(cdc20) inhibitor, links release from metaphase II arrest with the Ca(2+) transient and its degradation is triggered by the Ca(2...

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Detalhes bibliográficos
Main Authors: Levasseur, Mark, Dumollard, Remi, Chambon, Jean-Philippe, Hebras, Celine, Sinclair, Maureen, Whitaker, Michael, McDougall, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817944/
https://ncbi.nlm.nih.gov/pubmed/24194472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.096578
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