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Randomized Controlled Trial of Febuxostat Versus Allopurinol or Placebo in Individuals with Higher Urinary Uric Acid Excretion and Calcium Stones

BACKGROUND AND OBJECTIVES: Higher urinary uric acid excretion is a suspected risk factor for calcium oxalate stone formation. Febuxostat, a xanthine oxidoreductase inhibitor, is effective in lowering serum urate concentration and urinary uric acid excretion in healthy volunteers and people with gout...

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Главные авторы: Goldfarb, David S., MacDonald, Patricia A., Gunawardhana, Lhanoo, Chefo, Solomon, McLean, Lachy
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817901/
https://ncbi.nlm.nih.gov/pubmed/23929928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.01760213
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