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The ABCG8 G574R Variant, Serum Plant Sterol Levels, and Cardiovascular Disease Risk in the Old Order Amish

OBJECTIVE: To determine whether long-term exposure to moderate elevations in plasma plant sterol levels increases risk for atherosclerosis. METHODS AND RESULTS: In Old Order Amish participants aged 18 to 85 years, with (n=110) and without (n=181) 1 copy of the ABCG8 G574R variant, we compared mean p...

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Detalhes bibliográficos
Main Authors: Horenstein, Richard B., Mitchell, Braxton D., Post, Wendy S., Lütjohann, Dieter, von Bergmann, Klaus, Ryan, Kathleen A., Terrin, Michael, Shuldiner, Alan R., Steinle, Nanette I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817740/
https://ncbi.nlm.nih.gov/pubmed/23241408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.245480
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