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SCEDS: protein fragments for molecular replacement in Phaser

A method is described for generating protein fragments suitable for use as molecular-replacement (MR) template models. The template model for a protein suspected to undergo a conformational change is perturbed along combinations of low-frequency normal modes of the elastic network model. The unpertu...

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Detalles Bibliográficos
Autores principales: McCoy, Airlie J., Nicholls, Robert A., Schneider, Thomas R.
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817695/
https://ncbi.nlm.nih.gov/pubmed/24189233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444913021811
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