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High Payload Dual Therapeutic-Imaging Nanocarriers for Triggered Tumor Delivery

The in vitro and in vivo characterization of an optimized formulation of nanoparticles (NPs) loaded with a high content of dexamethasone palmitate (DEX-P), a chemotherapeutic adjuvant that decreases interstitial fluid pressure in tumors, and (111)In, a signaling agent, is described. These NPs are un...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Jin-Ki, Yuan, Hong, Nie, Jingxin, Yang, Yu-Tsai, Leggas, Markos, Potter, Philip M., Rinehart, John, Jay, Michael, Lu, Xiuling
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817621/
https://ncbi.nlm.nih.gov/pubmed/22777758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201200437
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