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Loss of Response to Long-Term Infliximab Therapy in Children with Crohn’s Disease

Secondary loss of response (LoR) often precludes further use of infliximab in children with Crohn’s disease. Immunomodulators may reduce the incidence of LoR but their combination with infliximab presents safety concerns. We aimed to determine the long-term durability of infliximab response in paedi...

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Hlavní autoři: Gouldthorpe, Oliver, Catto-Smith, Anthony G., Alex, George, Simpson, Di
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817600/
https://ncbi.nlm.nih.gov/pubmed/24275852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph6101322
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