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Oxygen Flux Analysis to Understand the Biological Function of Sirtuins

The sirtuins are a family of highly conserved NAD(+)-dependent lysine deacylases with important roles in metabolic regulation. Of the seven mammalian sirtuins, three localize to the mitochondria: SIRT3, SIRT4, and SIRT5. Mitochondrial sirtuins are crucial regulators of the metabolic network that con...

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Detalhes bibliográficos
Main Authors: Wang, Dongning, Green, Michelle F., McDonnell, Eoin, Hirschey, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817486/
https://ncbi.nlm.nih.gov/pubmed/24014411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-637-5_16
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