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Flexible synthesis of anthracycline aglycone mimics via domino carbopalladation reactions

A synthesis of anthracycline aglycone derivatives is described. The key step utilizes a powerful domino carbopalladation approach and subsequent ring closure. During this process two of the four rings of the anthracycline scaffold are formed. Differently substituted carbohydrates and dialkyne chains...

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Hlavní autoři: Leibeling, Markus, Werz, Daniel B
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817477/
https://ncbi.nlm.nih.gov/pubmed/24204433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.258
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