Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to pituitary dysfunction, neurodegeneration and development of obesity

MicroRNAs (miRNAs) have recently emerged as key regulators of metabolism. However, their potential role in the central regulation of whole-body energy homeostasis is still unknown. In this study we show that the expression of Dicer, an essential endoribonuclease for miRNA maturation, is modulated by...

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Detalhes bibliográficos
Main Authors: Schneeberger, Marc, Altirriba, Jordi, García, Ainhoa, Esteban, Yaiza, Castaño, Carlos, García-Lavandeira, Montserrat, Alvarez, Clara V., Gomis, Ramon, Claret, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817393/
https://ncbi.nlm.nih.gov/pubmed/24199146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2012.10.001
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