Alternative Signaling Pathways as Potential Therapeutic Targets for Overcoming EGFR and c-Met Inhibitor Resistance in Non-Small Cell Lung Cancer

The use of tyrosine kinase inhibitors (TKIs) against EGFR/c-Met in non-small cell lung cancer (NSCLC) has been shown to be effective in increasing patient progression free survival (PFS), but their efficacy is limited due to the development of resistance and tumor recurrence. Therefore, understandin...

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Detalhes bibliográficos
Main Authors: Fong, Jason T., Jacobs, Ryan J., Moravec, David N., Uppada, Srijayaprakash B., Botting, Gregory M., Nlend, Marie, Puri, Neelu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817236/
https://ncbi.nlm.nih.gov/pubmed/24223799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078398
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