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Mice with Chimeric Livers Are an Improved Model for Human Lipoprotein Metabolism
OBJECTIVE: Rodents are poor model for human hyperlipidemias because total cholesterol and low density lipoprotein levels are very low on a normal diet. Lipoprotein metabolism is primarily regulated by hepatocytes and we therefore assessed whether chimeric mice extensively repopulated with human cell...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3817217/ https://ncbi.nlm.nih.gov/pubmed/24223822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078550 |
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