Linear polyethylenimine produced by partial acid hydrolysis of poly(2-ethyl-2-oxazoline) for DNA and siRNA delivery in vitro

Polyethylenimines (PEIs) are the most efficient synthetic vectors for gene delivery available to date. With its high charge density and strong proton-buffering effect, PEI has an ability to condense DNA and small interfering RNA at physiologic pH. However, the polymer suffers from the disadvantage o...

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Hlavní autoři: Fernandes, Julio C, Qiu, Xingping, Winnik, Françoise M, Benderdour, Mohamed, Zhang, Xiaoling, Dai, Kerong, Shi, Qin
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2013
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817027/
https://ncbi.nlm.nih.gov/pubmed/24204139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S47413
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