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sCD44 overexpression increases intraocular pressure and aqueous outflow resistance

PURPOSE: CD44 plays major roles in multiple physiologic processes. The ectodomain concentration of the CD44 receptor, soluble CD44 (sCD44), is significantly increased in the aqueous humor of primary open-angle glaucoma (POAG). The purpose of this study was to determine if adenoviral constructs of CD...

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Detalhes bibliográficos
Main Authors: Giovingo, Michael, Nolan, Michael, McCarty, Ryan, Pang, Iok-Hou, Clark, Abbot F., Beverley, Rachel M., Schwartz, Steven, Stamer, W. Daniel, Walker, Loyal, Grybauskas, Algis, Skuran, Kevin, Kuprys, Paulius V., Yue, Beatrice Y.J.T., Knepper, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816995/
https://ncbi.nlm.nih.gov/pubmed/24194636
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