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DGKα DNA vaccine relieves airway allergic inflammation in asthma model possibly via induction of T cell anergy

Induction of T cell immune tolerance is thought to be a good method for treatment of asthma. Diacylglycerol kinases alpha (DGKα), enzymes that catalyze phosphorylation of diacylglycerol to produce phosphatidic acid, could inhibit diacylglycerol (DAG)-mediated signaling following T-cell receptor enga...

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Detalhes bibliográficos
Main Authors: Wang, Yan, Zhang, Qiao, Ma, Qianli, Zhang, Youlan, Li, Zhiwei, Wang, Changzheng
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816809/
https://ncbi.nlm.nih.gov/pubmed/24228102
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