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FasL on human nucleus pulposus cells prevents angiogenesis in the disc by inducing Fas-mediated apoptosis of vascular endothelial cells

The intervertebral disc is the largest avascular organ in the human body. However, with the progress of intervertebral disc degeneration (IDD), the disc tends to be vascularized increasingly via angiogenesis. It is well established that both human nucleus pulposus (NP) cells and vascular endothelial...

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Detalhes bibliográficos
Main Authors: Sun, Zhen, Wan, Zhong-Yuan, Guo, Yun-Shan, Wang, Hai-Qiang, Luo, Zhuo-Jing
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816806/
https://ncbi.nlm.nih.gov/pubmed/24228099
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