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Dual Roles for the Notch Target Gene Hes-1 in the Differentiation of 3T3-L1 Preadipocytes

The process of adipogenesis involves a complex program of gene expression that includes down-regulation of the gene encoding Hes-1, a target of the Notch signaling pathway. To determine if Notch signaling affects adipogenesis, we exposed 3T3-L1 preadipocytes to the Notch ligand Jagged1 and found tha...

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Detalhes bibliográficos
Main Authors: Ross, David A., Rao, Prakash K., Kadesch, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC381674/
https://ncbi.nlm.nih.gov/pubmed/15060169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.8.3505-3513.2004
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