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3,4-Dihydroxy-5-nitrobenzaldehyde (DHNB) is a Potent Inhibitor of Xanthine Oxidase: a potential therapeutic agent for treatment of hyperuricemia and gout

Hyperuricemia, excess of uric acid in the blood, is a clinical problem that causes gout and is also considered a risk factor for cardiovascular disease. The enzyme xanthine oxidase (XO) produces uric acid during the purine metabolism; therefore, discovering novel XO inhibitors is an important strate...

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Autors principals: Lü, Jian-Ming, Yao, Qizhi, Chen, Changyi
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816736/
https://ncbi.nlm.nih.gov/pubmed/23994369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.08.011
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