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Calcium Channel Blockers as Tocolytics: Principles of Their Actions, Adverse Effects and Therapeutic Combinations

Dihydropyridine Ca(2+) channel blockers (CCBs) are widely accepted in the treatment of premature labour. Their mechanism of action in tocolysis involves the blockade of L-type Ca(2+) channels, influenced by the Ca(2+)-activated K(+) channels, beta-adrenergic receptors (β-ARs) and sexual hormones. In...

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Detalhes bibliográficos
Main Authors: Gáspár, Róbert, Hajagos-Tóth, Judit
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816733/
https://ncbi.nlm.nih.gov/pubmed/24276256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph6060689
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