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Phorbol Ester Modulation of Ca(2+) Channels Mediates Nociceptive Transmission in Dorsal Horn Neurones
Phorbol esters are analogues of diacylglycerol which activate C1 domain proteins, such as protein kinase C (PKC). Phorbol ester/PKC pathways have been proposed as potential therapeutic targets for chronic pain states, potentially by phosphorylating proteins involved in nociception, such as voltage-d...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816730/ https://ncbi.nlm.nih.gov/pubmed/24276261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph6060777 |
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