Association of Rad9 with Double-Strand Breaks through a Mec1-Dependent Mechanism

Rad9 is required for the activation of DNA damage checkpoint pathways in budding yeast. Rad9 is phosphorylated after DNA damage in a Mec1- and Tel1-dependent manner and subsequently interacts with Rad53. This Rad9-Rad53 interaction has been suggested to trigger the activation and phosphorylation of...

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Bibliographic Details
Main Authors: Naiki, Takahiro, Wakayama, Tatsushi, Nakada, Daisuke, Matsumoto, Kunihiro, Sugimoto, Katsunori
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC381673/
https://ncbi.nlm.nih.gov/pubmed/15060150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.8.3277-3285.2004
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