ロード中...

A Potent (R)-alpha-bis-lipoyl Derivative Containing 8-Hydroxyquinoline Scaffold: Synthesis and Biological Evaluation of Its Neuroprotective Capabilities in SH-SY5Y Human Neuroblastoma Cells

A novel bis-lipoyl derivative containing 8-hydroxyquinoline scaffold (LA-HQ-LA, 5) was synthesized as a new multifunctional drug candidate with antioxidant, chelant, and neuroprotective properties for the treatment of neurodegenerative diseases. We have investigated the potential effectiveness of LA...

詳細記述

保存先:
書誌詳細
主要な著者: Cacciatore, Ivana, Fornasari, Erika, Baldassarre, Leonardo, Cornacchia, Catia, Fulle, Stefania, Di Filippo, Ester Sara, Pietrangelo, Tiziana, Pinnen, Francesco
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816678/
https://ncbi.nlm.nih.gov/pubmed/24275787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph6010054
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!