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The Liver as a Target Organ for Gene Therapy: State of the Art, Challenges, and Future Perspectives

The liver is a target for gene therapy of inborn errors of metabolism, of hemophilia, and of acquired diseases such as liver cancer and hepatitis. The ideal gene transfer strategy should deliver the transgene DNA to parenchymal liver cells with accuracy and precision in the absence of side effects....

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Detalles Bibliográficos
Main Authors: Jacobs, Frank, Gordts, Stephanie C., Muthuramu, Ilayaraja, De Geest, Bart
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816670/
https://ncbi.nlm.nih.gov/pubmed/24281341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph5121372
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