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Synthesis and COX-2 Inhibitory Activity of 4-[(E)-2-(4-Oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethenyl]benzene-1-sulfonamideand Its Analogs

Some novel 3-phenyl-2-[(E)-2-phenylethenyl]-3,4-dihydroquinazolin-4-one derivatives possessing para-sulfonamides groups on the phenyl ring of the 2-phenylethenyl moiety have been synthesized and their COX-2 inhibitory activity evaluated. The stuctures of the synthesized compounds were confirmed on t...

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Hlavní autoři: Hayun, Hudiyono, Sumi, Hanafi, Muhammad, Yanuar, Arry
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816667/
https://ncbi.nlm.nih.gov/pubmed/24281337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph5121282
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