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INHIBITION OF SMOOTH MUSCLE CELL MIGRATION AND NEOINTIMA FORMATION IN VEIN GRAFTS BY OVEREXPRESSION OF MATRIX METALLOPROTEINASE-3

OBJECTIVE: Saphenous vein grafts suffer from neointima formation following bypass surgery. Matrix metalloproteinases (MMPs) play important roles in this process. We examined MMP-3 for its therapeutic potential to prevent smooth muscle cell migration and neointima formation in venous bypass grafts us...

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Autors principals: Kallenbach, Klaus, Salcher, Rolf, Heim, Albert, Karck, Matthias, Mignatti, Paolo, Haverich, Axel
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816542/
https://ncbi.nlm.nih.gov/pubmed/19268777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2008.11.001
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