Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling.

The Brn-3 subfamily of POU domain genes are expressed in sensory neurons and in select brainstem nuclei. Earlier work has shown that targeted deletion of the Brn-3b and Brn-3c genes produce, respectively, defects in the retina and in the inner ear. We show herein that targeted deletion of the Brn-3a...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Xiang, M, Gan, L, Zhou, L, Klein, W H, Nathans, J
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC38164/
https://ncbi.nlm.nih.gov/pubmed/8876243
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki