Cyclotide Discovery in Gentianales Revisited—Identification and Characterization of Cyclic Cystine-Knot Peptides and Their Phylogenetic Distribution in Rubiaceae Plants

Cyclotides are a unique class of ribosomally synthesized cysteine-rich miniproteins characterized by a head-to-tail cyclized backbone and three conserved disulfide-bonds in a knotted arrangement. Originally they were discovered in the coffee-family plant Oldenlandia affinis (Rubiaceae) and have sinc...

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Autori principali: Koehbach, Johannes, Attah, Alfred F., Berger, Andreas, Hellinger, Roland, Kutchan, Toni M., Carpenter, Eric J., Rolf, Megan, Sonibare, Mubo A., Moody, Jones O., Ka-Shu Wong, Gane, Dessein, Steven, Greger, Harald, Gruber, Christian W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816352/
https://ncbi.nlm.nih.gov/pubmed/23897543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22328
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